Viral Whole Genome Analysis
Viral whole genome sequencing using the Oxford Nanopore methodology is a cutting-edge and innovative technique that enables comprehensive analysis of viral genetic material. Leveraging the power of Oxford Nanopore Technologies, this approach provides researchers and scientists with a high-resolution view of the complete viral genome
COVID-19 Analysis
Our customized pipeline for detection of SARS-CoV-2 based on Oxford Nanopore sequencing technology which utilizes the benefits of long reads. Our service aligns the reads to SARS-CoV-2 reference genome, calls variants, and generates a consensus genome sequence. It then determines lineage, clade and phylogenetic tree information of the sample using Pangolin and NextClade. All the information with its data and QC metric files gets summarized in one extensive html report for easy viewing.
More Accurate Results with Long Reads
Whole Genome Construction
Arctic Protocol Based Analysis
nCOV19 Genome Analyzer
Results and Post Analyzes
Influenza Analysis
Oxford Nanopore Technologies offers a workflow that enables Influenza A and B whole genomes to be amplified by PCR and run 96 different samples in a single flow cell using ligation sequencing chemistry.
Sequencing data of influenza samples are used with our automated analysis program to determine which subtype the Influenza genome belongs to via the Nextclade database (clades.nextstrain.org). The studied data are evaluated and reported with the vaccine strains of Influenza A and B virus types in this database.
Frequently Asked Questions (FAQ)
How should I send my sample?
The viral DNA/RNA isolation step is the most important step of your study. Success at this stage will affect the entire sequence output. It is therefore recommended to send your sample as DNA. For RNA viruses, cDNA conversion is of great importance to protect the sample during transfer.
I have no chance to isolate DNA. How can I send my sample?
The viral DNA/RNA isolation step is the most important step of your study. Success at this stage will affect the entire sequence output. Therefore, it is recommended to send your sample as DNA. If the isolation service is included, there is no guarantee for the success of the study.
Why is DNA isolation important for the viral whole genome?
The genome of viruses is considerably smaller than that of other microorganisms. Since other microorganisms in the sample containing the virus you want to study will also be sequenced during sequencing, most of the data obtained will not be included in the viral genome analysis. Depending on your sample type, the amount of data recommended for analysis will vary. Therefore, the DNA isolation kit used in the study is very important depending on your sample type.
How much data should I receive?
To get the desired depth of data in the viral genome, the formula for viral genome length x depth is used. However, in addition, the proportion of virus in your sample must be taken into account. Please contact our Sales Specialists to plan your study in detail.