Library Preparation
Library preparation to sequence any fragment length. Oxford Nanopore solutions offer a flexible, cost-effective way to generate high-quality data, whether studying the human genome, the microbiome, or life’s diversity. Tailored for specific research needs, these solutions streamline everything from whole-genome to targeted sequencing and beyond.
World’s Most Accesible High-Yield Sequencing Technology
Oxford Nanopore Technologies
Through the vision of “the analysis of anything, by anyone, anywhere” Oxford Nanopore Technologies (ONT) put forth a new generation of sensing technology.
Oxford Nanopore library preparation solutions are tailored to specific research needs, from whole-genome to targeted sequencing and beyond. As the distributor for Oxford Nanopore, Massive Bioinformatics offers solutions compatible with all nanopore sequencing devices, giving you the flexibility to select the most suitable option for your experiment.
Oxford Nanopore DNA and RNA library preparation
A wide range of library preparation kits is available to suit whole-genome as well as targeted sequencing requirements. Amplification-free kits allow direct sequencing of short to ultra-long fragments of native DNA, eliminating PCR bias and allowing the detection of base modifications alongside standard nucleotides. Amplification-based kits enable whole-genome sequencing from low-input amounts or low-quality DNA (e.g. FFPE).
The RNA library preparation kits offer a range of benefits, including high accuracy, long reads, and fast turnaround times. Every research project is unique, so to cater to different research projects, a range of kits are available.
Confidently characterise and quantify full-length RNA transcripts, splice variants, and fusions using short to ultra-long fragment nanopore sequencing. Accurately analyse differential gene expression and transcript usage. Sequence native RNA directly, without amplification or reverse transcription, and identify base modifications.
Library Preparation
A wide range of library preparation kits is available to suit whole-genome as well as targeted sequencing requirements. Amplification-free kits allow direct sequencing of short to ultra-long fragments of native DNA, eliminating PCR bias and allowing the detection of base modifications alongside standard nucleotides. Amplification-based kits enable whole-genome sequencing from low-input amounts or low-quality DNA (e.g. FFPE).
The RNA library preparation kits offer a range of benefits, including high accuracy, long reads, and fast turnaround times. Every research project is unique, so to cater to different research projects, a range of kits are available.
Confidently characterise and quantify full-length RNA transcripts, splice variants, and fusions using short to ultra-long fragment nanopore sequencing. Accurately analyse differential gene expression and transcript usage. Sequence native RNA directly, without amplification or reverse transcription, and identify base modifications.
Library Preparation: The Foundation for Your Discoveries
Native: PCR-free for direct DNA or RNA sequencing eliminating GC bias, retaining all the biological information including base modifications without extra library preparation or sample manipulation, reducing costs and preparation time.
Comprehensive: Any DNA and RNA fragment length (from 20 bp to 4 Mb+) to access whole genomes, targeted genomes, methylomes, structural variants, full-length transcripts, and more.
Scalable: Easily scalable (automatable on various liquid handlers) to meet diverse needs, ensuring consistent and reproducible results.
Versatile: Compatible with a wide range of sample types (DNA, RNA, and cDNA) for a variety of applications.
Streamlined: Quick, simple and robust workflows, typically with 5 to 20 minutes of hands-on time.
High quality: Designed for high output and minimal bias, ensuring reliable and accurate results.